Learn about Cancer Marker: Alpha Feto Protein medical tests, including what the tests are used for, why a doctor may order a test, how a test will feel, and what the results may mean.
Alpha-fetoprotein (AFP) is a protein produced in the liver of a developing fetus. During a baby's development, some AFP passes through the placenta and into the mother's blood. An AFP test measures the level of AFP in pregnant women during the second trimester of pregnancy.
An AFP blood test is used to check a developing fetus for risk of birth defects and genetic disorders, such as neural tube defects or Down syndrome. The AFP test is especially important for women who are at high risk of having children with birth defects who are 35 or older, family history of birth defects, have diabetes or taken harmful medication during pregnancies.This screening exam also tests your levels of:
If you aren’t pregnant, an AFP test can help to diagnose and monitor certain liver conditions, such as liver cancer, cirrhosis, and hepatitis. It can also help detect several other cancers, such as testes, ovaries, biliary tract, stomach or pancreas.
A blood sample drawn from a vein in your arm. You may want to wear a shirt with sleeves that can easily be rolled up to make it easier to collect the blood sample. Results are typically available within one to two weeks.
AFP level | Range | Indications |
---|---|---|
Normal | 0 to 8 ng/mL | - |
High | 500 to 1,000 ng/mL or more | Adults - A sign of certain kinds of cancer or liver disease. Other types of cancer may not show up on an AFP test. |
Pregnant woman - Neural tube defect in your developing baby. The test will be inaccurate if you’ve been pregnant for a longer or shorter period of time than you thought. |